Academic-Researcher Finis Terrae University Santiago, Region Metropolitana, Chile
Disclosure(s):
Sandra L. Lopez-Arana, PhD: No relevant financial relationship(s) with ineligible companies to disclose.
Objectives: This study aimed to assess whether the concentrations of 25-Hydroxyvitamin D were associated with sleep factors (obstructive sleep apnea, nighttime insomnia, unrefreshing sleep, sleepiness) among participants of the National Health Survey of Chile (ENS-2016-17).
Methods: 25-Hydroxyvitamin D were measured using chemiluminescence immunoassay in a subsample of women of childbearing age and the elderly (n=2,790). Vitamin D severe deficiency and deficiency was defined as < 30 nmol/L and 30-49.9 nmol/L, respectively. Sleep outcomes were measured by questionnaires. Associations between 25-Hydroxyvitamin D and sleep factors were determined using linear and logistic regressions.
Results: The prevalence of severe vitamin D deficiency was 17.4%, and 37.4% of participants were found to have vitamin D deficiency. Participants with severe deficiency or deficiency had higher rates of obstructive sleep apnea, nighttime insomnia, and unrefreshing sleep compared to those with normal concentrations of 25-Hydroxyvitamin D.
Conclusions: Vitamin D deficiency, including severe deficiency, is very common among the Chilean population. Additionally, our results suggest that vitamin D deficiency is associated with an increased likelihood of obstructive sleep apnea, nighttime insomnia, and unrefreshing sleep.
Funding Sources: This research was funded by the Concurso Fomento a la Vinculación Internacional para Instituciones de Investigación at Finis Terrrae University.
