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The Role of Diet in Supporting Bone and Muscle Health in Older Adults (Poster Theater Flash Session 9)

(PTFS09-07-25) The Effect of Resistance Training on Physical Function Is Associated With Changes in Serum Albumin Redox States in Middle-Aged and Older Japanese Adults

Monday, June 2, 2025
10:20 AM – 10:24 AM ET
Location: South Hall B (The Hub) - Poster Theater / Poster Board Number PT-6
Objectives: This study was aimed at examining the relationship between the fraction of human mercaptoalbumin in total serum albumin (f(HMA)), a novel protein nutritional indicator, and the effects of resistance training in healthy middle-aged and older Japanese adults.

Methods: The study included 43 (age = 67.3 ± 8.0 years, n = 10 males, n = 33 females) healthy community dwelling middle-aged and elderly individuals. They were engaged in a low-load, body-weight-based resistance training program using an elastic band twice a week for 12 weeks under supervision. Anthropometric data, 6-meter gait speed, blood biochemistry, and dietary macronutrient intake were collected before and after the training intervention. The relationships between serum nutritional parameters and gait speed or their rate of change were examined using multivariate linear regression analysis.

Results: Before intervention, f(HMA) showed a significant positive correlation with the usual gait speed (β = 0.326, P = 0.045) and maximum gait speed (β = 0.331, P = 0.036). The changing rate of maximal gait speed showed a significant positive correlation with the rate of increase in f(HMA) (β = 0.456, P = 0.004).

Conclusions: Serum f(HMA) increased simultaneously with improvements in locomotor function through resistance training in middle-aged and older adults.

Funding Sources: This work was also supported in part by the Morinaga Milk Industry Co., Ltd.