(LB01-17-25) Diabesity and Sarcopenia, Is There an Association in Chilean Elderly Population?

Objectives: To evaluate the relationship between diabetes and sarcopenia in elderly people from the Chilean National Health Survey

Methods: Study of 1515 (62.9% female), community-dwelling older Chileans from the Chilean National Health Survey, with data of type 2 diabetes (DM2) (Assessed through self-reported diagnosis) and obesity (Body mass index cut-off point >30Kg/m²) and diagnosis of sarcopenia (Evaluated using the algorithm of the European Working Group on Sarcopenia in Older People (EWGSOP1)), Diabesity is defined as the simultaneous diagnosis of DM2 and obesity, logistic regression models were performed to evaluate association.

Results: A prevalence of 8.84% of diabesity was detected and a 13.75% of sarcopenia without statistically significant differences by sex. When comparing the prevalence of sarcopenia between normal subjects (without DM2 or obesity), only DM2, only obesity and diabesity, we found statistically significant differences, being higher in participants with DM2 with 30.43% vs 17.34% in normal, 6.38% in obese and 3.7% in diabesity p< 0.001. In the fully adjusted model DM2 (OR=1.65; 95%CI:1.05-3.49) and age (OR=1.15;95%CI:1.10-1.20) was negative associated with Sarcopenia.

Conclusions: Chile is experiencing an advanced demographic transition characterized by an increase in life expectancy and in the prevalence of chronic diseases. Previous studies proposed that individuals with diabesity are susceptible to the acceleration of sarcopenia.
No negative association was found between diabesity and sarcopenia, possibly due to the number of people with diabesity, more studies are needed to establish the relationship between diabesity and sarcopenia in older Chileans.

Funding Sources: Attendance at the conference Universidad de La Frontera, INTA, Universidad de Chile
The Chilean National Health Survey was funded by the Chilean Ministry of Health (MINSAL Chile)