(P27-067-25) A Digital Home Device to Monitor Human Milk Maturation

Objectives: The objective of this study is to validate a novel, ta- home human milk conductivity sensing technology, real-time, non-invasive tracking of secretory activation process.

Methods: This retrospective study employed an innovative handheld milk conductivity sensing device to monitor sodium-linked milk maturation progress. The device's precision and accuracy were validated using standard KCl solutions and breast milk samples. User testing included 555 lactating mothers, each providing 0.3–0.5 ml milk samples from both breasts. Milk Maturation Percentage (MM%) was determined using a predefined algorithm based on conductivity measurements. Retrospective analysis explored correlations between milk conductivity, sodium levels, and other milk components. Additionally, preliminary predictive analysis evaluated the sensitivity of the MM% threshold in detecting cases of low milk supply between days 6 and 20 postpartum.

Results: The study demonstrated that the device is both precise and accurate in measuring milk conductivity, showing a strong correlation with sodium levels (r = 0.93, p < 0.001). The calculated Milk Maturation Percentage (MM%) exhibited a dynamic pattern throughout the process of lactogenesis, with notably lower MM% values observed in mothers who reported low milk supply or breastfeeding difficulties. Preliminary analysis identified the 15th percentile MM% threshold as a potential diagnostic marker, achieving 81% sensitivity and 79% positive predictive value in detecting cases of low milk supply between days 6 and 20 postpartum. Importantly, the device provided objective and real-time feedback to users, enabling early identification of delayed lactogenesis and breastfeeding challenges. These findings highlight the device's potential as a valuable tool for supporting lactation management and improving breastfeeding outcomes through timely intervention.

Conclusions: The device facilitates  early identification of lactation challenges, promoting breastfeeding success and enhancing maternal confidence.

Funding Sources: This research is in collaboration with MyMilk Laboratories Ltd.