Professor University of Florida Gainesville, Florida, United States
Disclosure(s):
Kaylyn E. Koons, MS: No relevant financial relationship(s) with ineligible companies to disclose.
Objectives: The aim of this study is to explore the relationships between hydration, nutritional status, and non-motor symptoms in people with PD.
Methods: A cross-sectional study will be conducted to evaluate hydration, nutritional status, and non-motor symptoms in 50 people with PD (50-90 years). Body composition, hydration, and phase angle will be assessed by bioelectrical impedance spectroscopy (BIS), handgrip strength by dynamometer, and resting metabolic rate by indirect calorimetry. Participants will complete the 12-question Gastrointestinal Dysfunction Scale in Parkinson’s Disease (GIDS-PD), the 9-question Gastroparesis Cardinal Symptom Index (GDSI), and a 24-hour recall of food and beverage intake, including a brief choline screener. Inclusion criteria include a self-disclosed diagnosis of Parkinson’s disease and consumption of an oral diet. Exclusion criteria include a pacemaker implant and joint replacement surgery. Descriptive statistics will summarize and describe the demographic and clinical characteristics of the study population. Correlations will assess relationships between continuous variables. Specifically, associations between hydration, nutritional status, and non-motor symptoms will be explored.
Results: In people with PD, we hypothesize that the severity of non-motor symptoms will be negatively correlated with muscle mass, and handgrip strength. The severity of non-motor symptoms will be associated with hydration status and dietary intake adequacy.
Conclusions: Gaining a clearer understanding of the interrelationships between non-motor symptoms, hydration, and nutritional status of people with PD may help refine management strategies, ultimately improving their nutritional status and quality of life.
Funding Sources: Norman Fixel Institute for Neurological Diseases; UF Health
